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Anthony Letai Selected Research

S63845

1/2021Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics.
1/2021ER+ Breast Cancer Strongly Depends on MCL-1 and BCL-xL Anti-Apoptotic Proteins.
12/2020Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia.

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Anthony Letai Research Topics

Disease

74Neoplasms (Cancer)
10/2022 - 09/2002
15Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2022 - 10/2012
13Leukemia
01/2022 - 11/2009
9Breast Neoplasms (Breast Cancer)
01/2021 - 10/2008
9Lymphoma (Lymphomas)
01/2021 - 04/2003
8B-Cell Lymphoma (Lymphoma, B Cell)
01/2019 - 08/2012
7B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2021 - 01/2007
5Multiple Myeloma
06/2022 - 11/2005
5Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 01/2017
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2019 - 02/2008
4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
01/2022 - 04/2013
4Lung Neoplasms (Lung Cancer)
01/2018 - 12/2007
4Carcinogenesis
05/2014 - 01/2008
3Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 10/2012
3Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
10/2020 - 08/2012
3B-Cell Leukemia (Leukemia, B Cell)
10/2016 - 01/2007
2Carcinoma (Carcinomatosis)
10/2021 - 11/2016
2Non-Hodgkin Lymphoma (Lymphosarcoma)
02/2021 - 09/2015
2Triple Negative Breast Neoplasms
01/2021 - 11/2020
2Infections
01/2020 - 01/2018
2Thrombocytopenia (Thrombopenia)
01/2020 - 08/2013
2Small Cell Lung Carcinoma (Small Cell Lung Cancer)
01/2019 - 06/2005
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/2021
1Aneuploidy (Aneuploid)
12/2020
1Febrile Neutropenia
01/2020
1Neutropenia
01/2020
1Nausea
01/2020
1Ovarian Neoplasms (Ovarian Cancer)
11/2019
1T-Cell Lymphoma (Lymphoma, T Cell)
01/2019
1Wilms Tumor (Wilm's Tumor)
01/2019
1Esophageal Neoplasms (Esophageal Cancer)
06/2018
1Sepsis (Septicemia)
01/2018
1Respiratory Insufficiency (Respiratory Failure)
01/2018

Drug/Important Bio-Agent (IBA)

39Proteins (Proteins, Gene)FDA Link
01/2021 - 04/2003
26venetoclaxIBA
04/2022 - 01/2013
8Pharmaceutical PreparationsIBA
11/2021 - 02/2015
6Biomarkers (Surrogate Marker)IBA
01/2019 - 09/2012
6Peptides (Polypeptides)IBA
01/2018 - 09/2002
6ABT-737IBA
08/2012 - 06/2005
5navitoclaxIBA
01/2021 - 08/2013
5Apoptosis Regulatory ProteinsIBA
01/2021 - 11/2009
4Azacitidine (5 Azacytidine)FDA Link
01/2021 - 01/2019
4Biological ProductsIBA
12/2016 - 10/2012
3S63845IBA
01/2021 - 12/2020
3Estrogen ReceptorsIBA
01/2021 - 01/2013
3Phosphotransferases (Kinase)IBA
01/2018 - 12/2017
3Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2018 - 12/2007
2RNA (Ribonucleic Acid)IBA
01/2022 - 01/2021
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2022 - 06/2014
2Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2022 - 01/2021
2ChromatinIBA
01/2022 - 01/2021
2Transcription Factors (Transcription Factor)IBA
01/2022 - 10/2020
2Drug CombinationsIBA
01/2021 - 01/2021
2DecitabineFDA Link
01/2021 - 01/2019
2ErbB Receptors (EGF Receptor)IBA
11/2020 - 12/2007
2taxaneIBA
11/2019 - 10/2008
2Phosphatidylinositols (Phosphatidylinositol)IBA
01/2019 - 06/2014
2Small Interfering RNA (siRNA)IBA
01/2017 - 05/2014
2Antineoplastic Agents (Antineoplastics)IBA
05/2014 - 10/2008
1antineoplaston A10 (A 10)IBA
01/2022
1GlucocorticoidsIBA
01/2022
1tofacitinibIBA
01/2022
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2021
1Immune Checkpoint InhibitorsIBA
01/2021
1A-1331852IBA
01/2021
1AlpelisibIBA
01/2021
1ipatasertibIBA
01/2021
1Etoposide (VP 16)FDA LinkGeneric
01/2021
1ABT-414IBA
11/2020
1Immunoconjugates (Immunoconjugate)IBA
11/2020
1tazemetostatIBA
10/2020
1Histone MethyltransferasesIBA
10/2020
1Lysine (L-Lysine)FDA Link
10/2020
1Ligases (Synthetase)IBA
11/2019
1UbiquitinIBA
11/2019
1tagraxofuspIBA
11/2019
1PlatinumIBA
11/2019
1Interleukin-3 Receptors (Interleukin 3 Receptor)IBA
11/2019
1Thalidomide (Thalomid)FDA Link
11/2019
1Vincristine (Oncovin)FDA LinkGeneric
01/2019
1ProteomeIBA
01/2019
1copanlisibIBA
01/2019
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2019
1ProhibitinsIBA
01/2019
1Tumor Biomarkers (Tumor Markers)IBA
01/2019
1Prednisone (Sone)FDA LinkGeneric
01/2019
1RNA Splicing FactorsIBA
10/2018
1Tyrosine Kinase InhibitorsIBA
01/2018
1Oxidoreductases (Dehydrogenase)IBA
01/2018
1Phosphoprotein Phosphatases (Phosphatases, Protein)IBA
01/2018
1Coenzyme A (CoA)IBA
01/2018

Therapy/Procedure

49Therapeutics
10/2022 - 09/2002
26Drug Therapy (Chemotherapy)
01/2021 - 01/2007
9Precision Medicine
10/2022 - 12/2015
2Immunotherapy
01/2022 - 01/2021
2Aftercare (After-Treatment)
01/2020 - 08/2012
1Combination Drug Therapy (Combination Chemotherapy)
11/2019
1Neoadjuvant Therapy
06/2018
1Esophagectomy
06/2018